Felicia Spitzer

PhD student

RESEARCH

My PhD research focuses on immunotherapy strategies and tumor monitoring for colorectal cancer. In relation to that I‘m investigating the roles of tumor-specific CD4 T cell responses and circulating tumor cells (CTCs) in preclinical cancer mouse models. Defining the phenotypes and functional characteristics of T cells in the tumor microenvironment and lymphoid organs, as well as the kinetics of CTCs in blood will allow me to better determine the effects of different immunotherapies, and improve the options for tumor and immune monitoring using CTCs.

CURRICULUM VITAE

I studied Biomedicine and Biotechnology at the University of Veterinary Medicine of Vienna and Molecular Biology at the University of Vienna. During my Bachelor and Master studies, I completed several internships working with animal models, oncology and immunology. For my Master’s thesis, I investigated the targets of CD4 T cell responses during multiple flavivirus infections. I started my PhD in November 2020 as a member of the EU Marie Skłodowska-Curie project “CAST”, and have been working in the laboratories of Prof. Katharina Pachmann (SIMFO, Germany) and Prof. Ferry Ossendorp (LUMC) since then.

Publications

  • Dynamics of CD4 T Cell and Antibody Responses in COVID-19 Patients With Different Disease Severity.

    Koblischke M, Traugott MT, Medits I, Spitzer FS, Zoufaly A, Weseslindtner L, Simonitsch C, Seitz T, Hoepler W, Puchhammer-Stöckl E, Aberle SW, Födinger M, Bergthaler A, Kundi M, Heinz FX, Stiasny K, Aberle JH.

    Frontiers in Medicine. 2020;7(771)

  • CD4 T Cell Determinants in West Nile Virus Disease and Asymptomatic Infection.

    Koblischke M, Spitzer FS, Florian DM, Aberle SW, Malafa S, Fae I, Cassaniti I, Jungbauer C, Knapp B, Laferl H, Fischer G, Baldanti F, Stiasny K, Heinz FX, Aberle JH.

    Frontiers in Immunology. 2020;11(16).

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