The immune system is directly or indirectly involved in health and many pathologies, two extreme ends being auto-immunity (such as rheumatoid arthritis) and hypo-immunity (in cancer). The dissection of the molecular wheelwork of immunology and the design and synthesis of molecules to specifically intervene in these processes have a significant impact in science and healthcare. This highly interdisciplinary field will deliver new chemistry-based fundamental research- and diagnostic tools, as well as novel classes of immune interventions and combination therapies.
Our multidisciplinary research group combines chemistry, protein engineering and immunology to design, synthesize and functionally characterize molecules and formulations to understand or manipulate the immune system. We aim to achieve targeted immunomodulation for chemistry-based precision immunotherapy.
