About the Tumor Immunology Group

Our major research theme is experimental cancer immunology. Fundamental and translational aspects of immune therapeutic strategies are studied, including T cell immunity, antigen processing and presentation, dendritic cell biology and cancer vaccine design.

Areas of interest

Cancer-specific CD4 and CD8 T cell immunity
Antigen presentation and dendritic cell biology
Molecularly defined cancer vaccines

News

Groups

Tumor biology and immunology

Our research aims to delineate cellular and molecular processes that govern adaptive immunity
Tumor Immunology

Immunotherapy of cancer: immunological mechanisms and specific therapeutic strategies
T cell regulation

We study the molecular and cellular regulation of T-cell responses and aim to use this knowledge to inform and improve immunotherapy
Transplant Immunology

Our research focuses on the prevention, detection and treatment of HLA sensitization in transplant recipients
Reproductive Immunology

We aim to understand how the pregnant woman immunologically tolerates her baby, and what mechanisms account for pregnancy complications
Complement and antibodies

From immunopathology to immunotherapy
Mucosal Immunology

We study the development and function of the mucosal immune system in health and disease
Stem Cells and Lymphocyte Development

Basic Science meets Gene Therapy
Molecular biology of innate immunity

Nucleic acid sensing in viral infection and sterile inflammation
Immune monitoring

Monitoring of immune cell populations during health, disease and (targeted) treatment
Peptide Immunology

Our research is focused on the application of synthetic peptides to solve medical problems

Collaborate with us

Looking for information on one of our topics, a new place to conduct your research or connect to experienced researchers to join forces with? Feel free to contact us!

About the Tumor Immunology Group

News

Frank Staal receives Rare Angel Award

Inspirational inaugural speech by Leendert Trouw

Corona vaccine maker and mRNA pioneer Uğur Şahin visits the LUMC

Groups

Tumor biology and immunology

Our research aims to delineate cellular and molecular processes that govern adaptive immunity

Tumor Immunology

Immunotherapy of cancer: immunological mechanisms and specific therapeutic strategies

T cell regulation

We study the molecular and cellular regulation of T-cell responses and aim to use this knowledge to inform and improve immunotherapy

Transplant Immunology

Our research focuses on the prevention, detection and treatment of HLA sensitization in transplant recipients

Reproductive Immunology

We aim to understand how the pregnant woman immunologically tolerates her baby, and what mechanisms account for pregnancy complications

Complement and antibodies

From immunopathology to immunotherapy

Mucosal Immunology

We study the development and function of the mucosal immune system in health and disease

Stem Cells and Lymphocyte Development

Basic Science meets Gene Therapy

Molecular biology of innate immunity

Nucleic acid sensing in viral infection and sterile inflammation

Immune monitoring

Monitoring of immune cell populations during health, disease and (targeted) treatment

Peptide Immunology

Our research is focused on the application of synthetic peptides to solve medical problems

Collaborate with us