Assistant Professor - Group leader
Dr. Michael Eikmans
Brief summary of research:
Michael Eikmans studied biology and received a PhD degree in 2002 at the department of Pathology of the LUMC on the topic of biomarkers in kidney diseases and transplantation. He was appointed as research fellow at the transplantation group (Prof. Bob Colvin) in the Massachusetts General Hospital in Boston MA. In 2006, he started working at the department of Immunology to perform research on immunological and molecular aspects of transplantation. He received various grants from the Dutch Kidney Foundation and the Roche Organ Transplantation Research Foundation, and also the Distinguished Research Award from the Dutch Transplant Society. Since 2016, his research shifted toward Reproductive Immunology, with a focus on immune mechanisms in mother and child during and after pregnancy. The research lines include study of immune regulation in healthy and complicated, spontaneously conceived pregnancies, and also in pregnancies after oocyte donation. Investigations on the frequency, nature, and consequences of pregnancy-induced maternal and fetal microchimerism are performed by his research group as well. Total output includes over 100 scientific articles (16 with IF>10).
Eikmans is a member of the Education Committee of the European Federation for Immunogenetics (EFI) and a Council Member of the European Society for Reproductive Immunology (ESRI). As Immunologist he is also performing on-call duties for clinical organ compatibility. Furthermore, he is actively involved in teaching Bachelor and Master students (Medical, Biomedical) in the fields of immunology, pregnancy, transplantation, and molecular biology.
Current and previous Positions:
2011-present Assistant Professor, Dept. of Immunology, LUMC, the Netherlands
2006-2010 Postdoctoral Researcher, Dept. of IHB, LUMC, the Netherlands
2003-2006 Postdoctoral Researcher, Dept. of Pathology, LUMC, the Netherlands
2002-2003 Research Fellow, Massachusetts General Hospital, Dept of Pathology, Boston MA
2001-2003 Junior Postdoc, Dept of Pathology, LUMC, the Netherlands
1997-2001 PhD Student, Dept of Pathology, LUMC, the Netherlands
Publications
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Identification of a unique intervillous cellular signature in chronic histiocytic intervillositis.
Krop J, van der Meeren LE, van der Hoorn MP, Ijsselsteijn ME, Dijkstra KL, Kapsenberg H, van der Keur C, Cornish EF, Nikkels PGJ, Koning F, Claas FHJ, Heidt S, Eikmans M, Bos M.
Placenta 139:34-42, 2023.
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The Mac Is Back: The Role of Macrophages in Human Healthy and Complicated Pregnancies.
Krop J, Tian X, van der Hoorn ML, Eikmans M.
Int J Mol Sci 24(6):5300, 2023.
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Imaging mass cytometry reveals the prominent role of myeloid cells at the maternal-fetal interface.
Krop J, van der Zwan A, Ijsselsteijn ME, Kapsenberg H, Luk SJ, Hendriks SH, van der Keur C, Verleng LJ, Somarakis A, van der Meeren L, Haasnoot G, Bos M, de Miranda NFCC, Chuva de Sousa Lopes SM, van der Hoorn MP, Koning F, Claas FHJ, Heidt S, Eikmans M.
iScience 25(7):104648, 2022.
Groups:
Tutors | Reproductive Immunology
