In 2012 I started working in the field of proficiency testing (EPT), as EPT scheme manager at the Eurotransplant Reference Laboratory for the organization of the Eurotransplant EPT in histocompatibility testing, including HLA-typing, HLA-antibody screening and crossmatching. In this position I am responsible for preparation and shipment of materials, assessment and report of results, publishing certificates and communication about EPT (related matters). Furthermore, I am involved in the continuous development of the EPT website for submission, assessment and reporting of results. I am co-organizer of the annual extramural meeting for tissue typing laboratories affiliated to Eurotransplant.
As EPT scheme manager, I was involved in the European Union funded EUROSTAM project, which was aimed at determining the feasibility and benefit of a Europe-wide Acceptable Mismatch Program for highly sensitized patients awaiting a kidney transplant.
Since 2014, I am a member of the EPT committee of the European Federation for Immunogenetics (EFI) and since 2016, I am the co-chair of this committee.
In 1993, I obtained my bachelor degree in Biochemistry at the Hogeschool Utrecht. From 1993-1997 I worked at the Clinical Genetics Department of the AZL, now LUMC. In 1997 I moved to the department of Immunology (formerly IHB) to start working in the tissue typing laboratory. After two years, I started combining this work with a research project which later became a fulltime job. This involved construction of a panel of Single Antigen Lines (SALs) that express only a single HLA antigen. These lines are used for screening of HLA-antibodies in highly immunized patients awaiting kidney transplant. Additionally, the panel was used for presence and role of HLA-C antibodies in immunized patients, the role of HLA-E in kidney transplantation and heterologous immunity.
Currently I work as EPT scheme manager within the Eurotransplant Reference Laboratory. Next to this I still am involved in material processing for the LUMC Transplant Center Biobank and management/maintenance of the SAL panel.