Thesis Defence Douwe Bosma

March 31, 2026

Thesis Defence	April 22 2026, 14:30 AM
PhD Student	Douwe Menno Tjebbe Bosma
Title	The power of Help: Mechanistic insights into CD4⁺ T cell differentiation in vaccination and cancer
Thesis advisors	Prof. dr. J.G. Borst - Dr. F. Salerno

Groups

Arens Lab / T cell regulation

We study the molecular and cellular regulation of T-cell responses and aim to use this knowledge to inform and improve immunotherapy
Eikmans Lab / Reproductive Immunology

We aim to understand how the pregnant woman immunologically tolerates her baby, and what mechanisms account for pregnancy complications
Heidt & Roelen Lab / Transplant Immunology

Our research focuses on the prevention, detection and treatment of HLA sensitization in transplant recipients
Ossendorp Lab / Tumor Immunology

Immunotherapy of cancer: immunological mechanisms and specific therapeutic strategies
Salerno Lab / Molecular Immunoregulation

We investigate the molecular mechanisms governing adaptive immunity, with a focus on post-transcriptional regulation of T cell function in health and disease.
Smits Lab / Infection and Lung Immunology

Impact of commensals and pathogens on inflammatory events in the lung
Staal Lab / Molecular Stem Cell biology and lymphoid development

Basic Science meets Gene Therapy
Trouw Lab / Complement and antibodies

From immunopathology to immunotherapy
Van der Maaden Lab / Pharmaceutical Immunology

Fusing pharmaceutical sciences and immunology to create transformative vaccines and delivery technologies for T cell induction and immune modulation, with a primary focus on cancer
Van der Veen Lab / Nucleic acid immunity

Nucleic acid sensing in viral infection and sterile inflammation
Van Unen Lab / Mucosal Immunology

We study the development and function of the mucosal immune system in health and disease
Verdoes Lab / Chemical Immunology

The development of chemical tools to understand and to manipulate the immune system
Xiao Lab / Dendritic Cell Biology & Tumor Immunology

Understanding mechanisms of DC licensing and T-cell function in the tumor microenvironment

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