The focus of the meeting was on intracellular pathways that mediate virus sensing and antiviral effector mechanisms. Amongst the highlights were keynote lectures from John Hiscott (Institute Pasteur) and Volker Thiel (University of Bern) as well as many other excellent talks (for the full program, click here). There was a lively poster session and a jury selected two poster prize winners who were both awarded a travel grant. The event was sponsored by the NWO, LIFI, LUMC, and an EU Horizon 2020 twinning project (Epiviral). After this highly successful and well-received first edition we will certainly repeat this event!